Melanocortin Peptides

Melanocortin peptides act on the MC1 to MC5 receptor family, which controls pigmentation, appetite, inflammation and sexual function. This collection covers broad and selective agonists for laboratory research only.

Selective versus broad agonists
Melanotan II acts on several melanocortin receptors. Melanotan I (afamelanotide) is more selective for MC1R in skin. PT-141 is studied for central MC4R and MC3R activity, and setmelanotide is designed to be selective for MC4R.

Common research uses
Pigmentation and photoprotection research uses MC1R agonists, while appetite and arousal research focuses on MC4R in the hypothalamus.

In this collection: Setmelanotide 10mg, PT-141 (Bremelanotide) 15mg, PT-141 (Bremelanotide) 10mg, Melanotan II 17mg, Melanotan I 13mg.

Is PT-141 the same as Melanotan II?
No. PT-141 is a metabolite of Melanotan II with a narrower, central receptor profile.

Which melanocortin peptide is MC4R-selective?
Setmelanotide.

All products are sold for laboratory research use only. Not for human or veterinary use.